Resident Population in Luzerne County, PA was 327.38800 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Luzerne County, PA reached a record high of 349.30000 in January of 1972 and a record low of 310.93700 in January of 2006. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Luzerne County, PA - last updated from the United States Federal Reserve on May of 2024.