Unemployment Rate in Guilford County, NC was 4.20% in February of 2024, according to the United States Federal Reserve. Historically, Unemployment Rate in Guilford County, NC reached a record high of 15.80 in April of 2020 and a record low of 1.90 in December of 1998. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Guilford County, NC - last updated from the United States Federal Reserve on May of 2024.